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             clINIcAl RcT STUDY

             The double-blind RCT study compared  whereas  none healed  in the control
             effects  of  PVR  System  to  standard  group. In the experimental  group the
             wound care treatment that the placebo  mean wound surface decreased by 96%
             group was simultaneously undergoing.  and volume by 99% while in the placebo
             Results  revealed  significantly  faster  group the mean surface decreased by

             healing time: 20 of the 30 wounds in the  25% and mean volume by 27%.
             experimental group healed in 4 weeks

             The effect of transcutaneous application of gaseous CO 2 on
             diabetic chronic wound healing-A double-blind randomized
             clinical trial
             Milos Macura, Helena Ban Frangez, Ksenija Cankar, Miha Finžgar, Igor Frangez

             PMID: 32633896 DOI: 10.1111/iwj.13436
             Int Wound J . 2020 Jul 7.

             Effect  of  transcutaneous  application  of  gaseous  carbon
             dioxide on cutaneous microcirculation

             Clin Hemorheol Microcirc. 2015;60(4):423-35.
             Miha Finzgar, Ziva Melik, Ksenija Cankar
             PMID: 25261433 DOI: 10.3233/CH-141898

             Use of  Transcutaneous  Application  of  cO2 in  Diabetic Foot


             Igor Frangez1, Jure Colnaric and Danijela Truden
              Clin Res Foot Ankle, Vol 5(2): 232 DOI: 10.4172/2329-910X.1000232

             The Effect of Transcutaneous Application of Gaseous CO2 on
             Diabetic Symmetrical  Peripheral Neuropathy—A Double-blind

             Randomized clinical Trial
             Helena Ban Frangež, Zoran Rodi, Jana Miklavčič, Igor Frangež
              Appl. Sci. 2021, 11(11), 4911 - DIABETIC FOOT,  27 May 2021
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