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4. CASE STUDIES

 ANGIOGENESIS

 Three case studies: Capillaroscopy and MR Image
 Acquisition

 Author: Dr. Ksenija Cankar, Institute of Physiology, Faculty of Medicine, University of
 Ljubljana, Ljubljana, Slovenia

Capillaroscopy
Capillaroscopy was performed by Mediscope Digital Video Microscope (Optilia,
Sweden). 100x magnification was used. Images were obtained at nailfold skin and at
the edge of the wound before and after treatments with PVR System. In each image
capillary density was measured.

          Before PVR System therapy                   After PVR System therapy

Wound 1                                               Nailfold skin             Capillary
                                                                                density
Nailfold skin				 Capillary                                                     36/mm2

                                             density
                                             24/mm2

Edge of the         Capillary                         Edge of the               Capillary
wound               density                           wound                     density
                    25/mm2                                                      28/mm2

Wound 2

Nailfold  skin				  Capillary                         Nailfold skin             Capillary
                    density                                                     density
                                                      Edge of the               64/mm2
                    40/mm2                            wound
                                                                                Capillary
Edge of the         Capillary                         Nailfold skin             density
wound               density                                                      31/mm2
                    14/mm2                            Edge of the
                                                      wound                     Capillary
Wound     3         Capillary                                                   density
Nailfold  skin				  density                                                     70/mm2

                    38/mm2                                                      Capillary
                                                                                density
Edge of the         Capillary                                                   24/mm2
wound               density
                    12/mm2
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